Nachitin is a professional adhesion prevention product developed by Yantai Wanli Medical Equipment Co., Ltd. through 5 years of development. Nachitin is with a long clinical history and substantial proof of safety and efficacy and it has been used in over 3,000,000 anti-adhesion procedures worldwide since it was introduced in 2003. Natchitin won the Chinese national invention patent In 2004. Yantai Wanli is also the only manufacturer in China that can produce two types of postoperative anti-adhesive dosages: film and gel. Since 2011 Natchitin has been exported to the European market.

Unique Features and Benefits: Ready to use, easy to handle in endoscopy surgery or open surgery. Provides a effective physical barrier to inter-tissue adhesions Resorbable 14days to provide complete coverage during the critical period of inflammation. Inhibits fibroblast grow on and around structures. Preventing adhesion in surgical intervention area and remote locations in entire abdominal pelvic cavity. Single composition,conforms to organs,patient rehabilitation is facilitated. Recurrent pain is reduced & the number of re-operations due to adhesions is reduced.

Sahin M, Cakir M, Avsar FM, Tekin A， Department of General Surgery, Meram Medical Faculty, Selcuk University Konya, Turkey Department of Surgical Emergency, Ankara Numune Research and Training Hospital, Ankara, Turkey
Aim: The purpose of this study is to compare the effects of different anti-adhesion materials in preventing postsurgical peritoneal adhesion.
Materials and Methods: 60 rats from Wistar Albino spiece that weights 250-300 g and about 10-11 ages are used in the study. They were separated into 5 groups. The rats were operated after Kethamine HCL anesthesia. In all rats, a midline laparatomy was done, in a 4 cm length. To the right side of the abdominal wall, 2 cm along 10 parellel incision were applied. To the left side of it, a peritoneum layer was incised as 2x2cm . The abdominal wall was sutured with 3/0 silk by continue method. Group I: Control group, Group II: 3x3cm2 in size Chitin layers (Nachitin®) were placed on the incision areas. Group III: 3x3 cm2 in size Na-Hyaluronat/Carboxymethylcellulose layers (Seprafilm) were placed on the incision areas. Group IV: To the abdominal cavity, 25% diluted 2 cc Na-Hyaluronat gel was poured, Group V: 15mg/kg metilprednizolon was injected as I.M. On the 11th day of research, under ketamine anesthesia, abdominal wall opened and the adhesions were scored according to Granat score.

From all groups of rats, blood samples were taken. On the samples, Hb, AST, BUN and albumin levels were studied.
Findings: The adhesion frequency in group I, was defined on the right abdominal wall as 82%, on the left as 91%. In group II, on the right as 8.3%, on the left as 25%. In group III, on the right as 17%, on the left as 33%. In group IV, on the right as 50%, on the left as 58%. In group V, on the right as 50%, on the left as 42%. The adhesion grade in groups was defined as; Group I: 2.63±1.22, Group II: 0.58±0.66, Group III: 1.08±1.08, Group IV: 1.41±1.44, Group V: 1.41±1.50. The adhesion phase in all study groups was found meaningfully low compared to the control group as p<0.05. Besides, the adhesion grade of Nachitin® group was found meaningfully low compared to the other groups as p<0.05. A meaningful difference was not observed among serologic and hematological parameters in all groups as P>0.05.
Results: Nachitin® lowers meaningfully the postoperative peritoneal adhesion frequency and adhesion grade on rats. Referencing this, it has been understood that Nachitin is much more effective than local and systemic anti-adhesive methods.